This one starts off somewhat promisingly, with a pretty fun twist on a standard vamp attack, but it quickly turns into one of those straight to cable B-movies where the director seems to want to keep the likes of USA Channel open as possible outlets. In other words, a strip club in which the girls don't take anything off. There's some mild gore, but in these days of Walking Dead, it's pretty tame stuff.
The plot is that a crazy preacher who likes to harass strippers gets himself turned into a vamp. He takes his "resurrection" as a sign that he's Christ's anointed one, and he turns a small posse of his redneck congregation into his vamp henchmen. Then he kidnaps the sweet-but-tuff new stripper, apparently because he wants her to be his queen. Brooding strip club bouncer "Fortune" (think poor man's Jason Patric) then teams up with some other vamp who pretty much enters the movie out of nowhere, and they storm the rural chapel to save the girl.
It's an oddly paced movie--the director spends more time on character development than you'd expect in such a cheaply made genre flick, and indeed the acting isn't horrible. The relationship between the young stripper and her daughter is pretty good, and the central preacher guy is manic and creepy. Spouting scripture through fangs is just a cool conceit. Still, this character development comes at the expense of pacing, so even though stuff is often happening, it feels like a long 90 minutes.
Overall,Southern Gothic is probably a little better made than most in it's class (budget $900k), but not good enough to recommend seeking out. Though if you're hitting up the horror strip club sub-genre, or the preacher/killer one, it's worth a look.